Peony
water-colour painting by Albrecht Dürer, approx. 1500
Adamus Lonecerus (physician in Frankfurt in the mid 17th century) writes the following on the peony:
"The root, worn round the neck/is good for the falling sickness."
Peony seeds (e.g. worn as a necklace) and peony leaves (as an infusion) were also used to prevent seizures.